HL and Breast Cancer
Adolescent girls treated for Hodgkin lymphoma (HL) are at considerable risk of developing breast cancer, based on results from an observational study. This study was undertaken in Germany and was based on long-term observation of 590 female patients from German-Austrian paediatric clinical trials undertaken between 1978 and 1995.
Patients were followed for an average of 17.8 years. Of the 590 patients, 19%, who had been treated with radiotherapy for their HL, developed breast cancer within 30 years. Among women aged 25 to 45 years, the incidence of breast cancer was found to be 24 times higher than that in the corresponding normal population. For more information, click here.